Daphne And Irina. Show 1 [UPDATED]
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Filming for season 2 started on 21 May 2018 to September 2018 in the Cote d'Azur, Monza,[15] Nice, and Monaco[16] for a 2019 release. Joining the show are Will Arnett, Juliet Stevenson, Poppy Delevingne, Jack Fox and Grégory Fitoussi, returning cast include Julia Stiles, Lena Olin, Roxane Duran and Dimitri Leonidas.[17]
Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related death. The biologic processes contributing to TRALI are poorly understood. All blood products can cause TRALI, and no specific treatment is available. A "2-event model" has been proposed as the trigger. The first event may include surgery, trauma, or infection; the second involves the transfusion of antileukocyte antibodies or bioactive lipids within the blood product. Together, these events induce neutrophil activation in the lungs, causing endothelial damage and capillary leakage. Neutrophils, in response to pathogens or under stress, can release their chromatin coated with granule contents, thus forming neutrophil extracellular traps (NETs). Although protective against infection, these NETs are injurious to tissue. Here we show that NET biomarkers are present in TRALI patients' blood and that NETs are produced in vitro by primed human neutrophils when challenged with anti-HNA-3a antibodies previously implicated in TRALI. NETs are found in alveoli of mice experiencing antibody-mediated TRALI. DNase 1 inhalation prevents their alveolar accumulation and improves arterial oxygen saturation even when administered 90 minutes after TRALI onset. We suggest that NETs form in the lungs during TRALI, contribute to the disease process, and thus could be targeted to prevent or treat TRALI.
Interpretation: Our results show normative values for pharyngeal swallowing and oesophageal motility in healthy volunteers. Detailed analysis of HRM data acquired during an STM shows that the rate-limiting factor for intake of solids in health is the frequency of pharyngeal swallowing and not oesophageal contractility. The reverse is true in patients with oesophageal motility disorders, in whom the frequency of effective oesophageal contractions determines eating speed.
If models were show dogs, Brad would be a golden retriever. He has a strong jaw, hazel eyes and thick blond hair that seems perpetually windswept. The scruff on his face is shaped carefully, deliberately, to draw attention to his cheekbones.
The leading lady of season 2 is played by British actress Simone Ashley. The 26-year-old is best known for playing popular girl Olivia on the Netflix comedy Sex Education, and she's also appeared in the British shows The Sister, Casualty, and Broadchurch, as well as the film Pokémon Detective Pikachu.
Bailey was an accomplished English actor even pre-Bridgerton, with roles on Broadchurch, Jack Ryan, and the Phoebe Waller-Bridge show Crashing. He's also a musical theater actor, having won a Laurence Olivier Award for his role in the 2018 West End revival of the musical Company. Since season 1, the actor appeared as a guest judge on RuPaul's Drag Race: UK vs the World, and is now starring in the play Cock alongside Rocketman's Taron Egerton.
In season 2, the eldest Bridgerton child applies the intensity he showed during his sister Daphne's season to his own search for a bride. Once he decides on Edwina Sharma as his future bride, he has to deal with Kate, and finds himself drawn to the elder Sharma even though she infuriates him.
Conn is best known on this side of the pond for starring in the Lifetime series Mistresses and The Lottery, as well as the short-lived Fox show Terra Nova. She also starred in the BBC show Liar alongside Downton Abbey's Joanne Froggatt. Next up after Bridgerton, she'll be joining the Prime Video fantasy series Good Omens.
The 32-year-old Brit has mostly stayed busy with Bridgerton, though she has an extensive back catalog if you want to watch some of her old shows. She previously starred on the British series Vanity Fair and Defending the Guilty, along with guest-starring roles on Lovesick, Call the Midwife, and Doctor Who.
The star of season 1 has been hard at work since the blockbuster success of Bridgerton, with tons of projects in the works (and a celebrity romance (opens in new tab) behind her). Some of the films and TV shows she's working on include a UK remake of the acclaimed French comedy Call My Agent!, a TV adaptation of Irish writer Naoise Dolan's novel Exciting Times, a thriller called Fair Play where she'll be co-starring alongside Alden Ehrenreich, and another thriller called I Heart Murder directed by Ingrid Goes West's Matt Spicer.
Though Daphne may have a husband and baby at home, she still shows up for important family events, including Eloise's introduction to society and the annual Bridgerton pall mall game. She also lends plenty of advice to Anthony as he searches for a wife.
Before landing his role as the third-born Bridgerton, Newton was best known for his role in Disney's UK show The Lodge and the teen show The Cut. He's mostly been devoted to Bridgerton since the show's success, as his character grows toward starring in his own love story (depicted in Julia Quinn's 4th book Romancing Mister Bridgerton).
Drysdale has been a fixture on British TV for over two decades, having starred on the sitcom Two Pints of Lager and a Packet of Crisps for eight seasons. She also is well known for playing Meghan Markle in the comedy soap The Windsors, based on the royal family (which is available on Netflix (opens in new tab) if you want to check it out). Since Bridgerton season 1 she has mostly done voice work on shows and podcasts, including the cartoon Circle Square.
A leading neurological hypothesis for autism postulates amygdala dysfunction. This hypothesis has considerable support from anatomical and neuroimaging studies. Individuals with bilateral amygdala lesions show...
Signaling mechanisms mediated by the Transforming Growth Factor-β (TGF-β) superfamily regulate a variety of developmental processes. Here we show that components of both bone morphogenetic protein/growth diffe...
***TUNE-IN ALERT*** WEDNESDAY, AUGUST 14THEGOT WINNER JOHN LEGEND AND RAPPER COMMON GUEST STAR IN AN ALL-NEW EPISODE OF VARIETY SKETCH SHOW, "SHERMAN'S SHOWCASE"AT 10:00 PM ET/PT ON IFCTHURSDAY, AUGUST 15THJEFF'S LOYALTY TO GEORGINA IS PUSHED TO ITS LIMITS ON AN ALL-NEW EPISODE OF SUNDANCE NOW'S "RIVIERA" SEASON TWOSUNDAY, AUGUST 18THMORGAN AND GRACE FIGHT FOR SURVIVAL ONAN ALL-NEW EPISODE OF "FEAR THE WALKING DEAD" SEASON 5AT 9:00PM ET/PT ON AMCJESSE'S MISSION TO AUSTRALIA MAY BE OVER BEFORE IT EVEN STARTED ON AN ALL-NEW EPISODE OF AMC'S OUTRAGEOUS DRAMA "PREACHER"AT 10:10 PM ET/PT ON AMCMONDAY, AUGUST 19THCHESTER LOOKS FOR ANSWERS WHEN TERMINAL ISLANDERS ARE EVICTED ON AN ALL-NEW EPISODE OF AMC'S ANTHOLOGY SERIES "THE TERROR: INFAMY"AT 9:00 PM ET/PT ON AMCLIZ GOES TO BATTLE FOR THE DUDLEY NAME ONAN ALL-NEW EPISODE OF AMC'S CRITICALLY ACCLAIMED SERIES "LODGE 49" SEASON TWOAT 10:01PM ET/PT ON AMCThis week on AMC Networks, all-new episodes of "Sherman's Showcase," "Fear the Walking Dead," "Lodge 49," "The Terror: Infamy," "Riviera," and "Preacher." Season one of IFC's "Sherman's Showcase" continues with an all-new episode on Wednesday, August 14th at 10pm ET/PT. On the fourth episode, "Enemies," Sherman reflects on his many haters over the decades as we dig into the rivalries and feuds of The Showcase. Turns out, genuine friendship is a rare commodity in showbiz, especially if you're talking about frenemies John Legend and Common.Each episode of "Sherman's Showcase" is hosted by Sherman McDaniels (Salahuddin) as he takes viewers through time via music and comedy drawn from the 40-year library of a legendary (but fictional) musical variety show, drawing inspiration from Solid Gold, Soul Train and Rowan & Martin's Laugh-In. Whether it's a questionably-attired funk super group in the 1970s, an up-and-coming MC in the 1980s or an R&B diva from the 1990s, Sherman's Showcase has it all: music, comedy, gameshow segments, political roundtables, commercial parodies, breakout hits destined to climb the charts, a dancing robot and a legendary host who's been there from the beginning.Diallo Riddle and Bashir Salahuddin serve as executive producers on "Sherman's Showcase" along with John Legend, Mike Jackson and Ty Stiklorius through their Get Lifted Film Co. (Underground, Jesus Christ Superstar) and Frank Scherma and Jim Bouvet of RadicalMedia (Stan Against Evil, Conversations With a Killer: The Ted Bundy Tapes). Season two of Sundance Now's "Riviera," continues on Thursday, August 15th. On this week's episode, Georgina (Juila Stiles) learns surprising news about Nico (Jack Fox) - but as she hones in on the proof, events take a horrifying turn. Jeff's (Will Arnett) loyalty to Georgina is pushed to its limit, while Irina threatens to crack under pressure as the family's suspicions grow."Riviera's" highly anticipated return picks up in the immediate aftermath of the explosive first series finale, where the Clios family is faced with the tragic death of one of their own. Only this time, the blood is on the hands of our female protagonist, Georgina.As Georgina tries to find a way to live with her crime, secrets from her past wash up on the sandy shores of the Cote d'Azur that force her to explore her turbulent childhood against her will. Following an unprecedented and unavoidable visit to her childhood home, Georgina returns with a refreshed sense of self to re-establish her power and position in the family alongside her charismatic confidant, uncle Jeff (Will Arnett).Georgina very quickly becomes acquainted with the Eltham family, an English dynasty that sail in to the Cote d'Azur providing its shores with a dose of new money and glamour. She goes on to form relationships with the whole family, some that appear genuine from the outset and others that unravel around her as secrets, old and new, become exposed. Juliet Stevenson takes on the role of Lady Cassandra Eltham and is joined on the Riviera by her children, the impossibly stylish Daphne (Poppy Delevingne) and the brooding Nico (Jack Fox) and Daphne's husband Raafi (Alex Lanipekun).Elsewhere in the Riviera, the rest of the Clios family is still reeling from Constantine's death. Christos (Dimitri Leonidas) is on the brink of losing everything, Adriana (Roxanne Duran) loses herself in a dangerous affair and Irina struggles to find her lost son, Adam.The Riviera has never been so tempestuous. Torn between her past and her present, can Georgina navigate her way to safer waters or will she lose her place in a world that she has grown to control? "Fear the Walking Dead" season five continues on Sunday, August 18th at 9:00 p.m. ET/PT. In this week's episode, "210 Words Per Minute," Morgan and Grace search an abandoned shopping mall for supplies and to fulfill a dying man's wish. There, the mission quickly turns into a fight for survival. Meanwhile, Dwight's resolve to be a better man is tested.In the second half of Season five, after successfully proving their way can work, our heroes gain momentum, rescuing survivors, and spreading the message of hope along the way -- until foes both familiar and unexpected arise, forcing the group to question whether their brand of altruism can really make a difference in a world filled with death and decay. "Preacher" season four continues on Sunday, August 18th at 10:10 p.m. ET/PT. On the fourth episode, "Search and Rescue," Tulip teams with Jesus Christ to plumb Masada's dungeons to free whatever remains of Cassidy. Meanwhile, Jesse's mission to Australia may be over before it's even started - as he picks himself up from the wreckage of his travels and finds he's stranded."Preacher" stars Dominic Cooper, Academy Award(R) nominee Ruth Negga and Joseph Gilgun, along with series regulars Ian Colletti, Graham McTavish, Pip Torrens, Julie Ann Emery, Noah Taylor, Mark Harelik and Tyson Ritter. As the series inches closer to the finale, God's endgame for the universe begins to click into place. Trapped between heavenly prophecies, hellish prisons, and all-out nuclear war, Jesse, Tulip, and Cassidy make their bloody way to the Most High. Whether they can reach God in time - or whether all this carnage is part of His divine plan - will soon be revealed as "Preacher" barrels towards the end of the world. The Sony Pictures Television and AMC Studios co-production was developed for television by executive producer and showrunner Sam Catlin ("Breaking Bad") and executive producers Seth Rogen and Evan Goldberg ("Sausage Party," "This is the End," "Superbad"). The series is also executive produced by James Weaver for Point Grey Pictures, Neal H. Moritz, Ori Marmur, Vivian Cannon, Jason Netter, Michael Slovis, Mark McNair, Garth Ennis, Ken F. Levin and Sara Goodman. "The Terror: Infamy" continues on Monday, August 19th at 9:00 p.m. ET/PT with an episode titled "All the Demons Are Still in Hell." In the wake of Pearl Harbor, the Terminal Islanders are evicted from their homes by the US Army and must find shelter elsewhere. While Henry, separated from his family, faces injustice at the hands of the government, Chester engages in a paranoid search for answers surrounding the mysterious events of the past weeks."The Terror: Infamy" centers on a series of bizarre deaths that haunt a Japanese American community, and a young man's journey to understand and combat the malevolent entity responsible. In addition, the series is one of the first depicting the internment of Japanese Americans on such a massive scale - complete with authentically recreated camps in scope and scale as post-WWII.The series stars Derek Mio, Kiki Sukezane (Lost in Space), Cristina Rodlo (Miss Bala), Shingo Usami (Unbroken), Naoko Mori (Everest), Miki Ishikawa (9-1-1) and renowned actor, producer, author and activist George Takei (Star Trek), who also serves as a consultant."The Terror: Infamy" is an AMC Studios production produced by Scott Free, Emaj Productions and Entertainment 360. In addition to Woo and Borenstein, Ridley Scott, David W. Zucker, Alexandra Milchan, Scott Lambert, Guymon Casady and Jordan Sheehan also serve as executive producers. "Lodge 49" season two continues on Monday, August 19th at 10:01 p.m. ET/PT. On the second episode, "The Slide," Dud makes an enemy cleaning pools, while Liz tries to hit bottom and a game of golf jeopardizes Ernie's career.Season two of this modern fable set in Long Beach, CA centers on likable "Squire" and ex-surfer Sean "Dud" Dudley (Wyatt Russell), whose beloved fraternal order -- the Ancient and Benevolent Order of the Lynx -- is suffering under new rule by an ill-suited leader. Despite his "Knight" and mentor Ernie's (Brent Jennings) lost faith, and his twin sister Liz's (Sonya Cassidy) struggle with their past, Dud believes he is the key to restoring the Lodge to its former grandeur and putting the rightful king on the throne. In addition to Russell, Jennings and Cassidy, this season's cast includes Linda Emond (Connie), Eric Allan Kramer (Scott) and David Pasquesi (Blaise). Jim Gavin (Author, Middle Men) serves as creator, writer and executive-producer alongside showrunner Peter Ocko (Pushing Daisies, The Office). Additional executive producers include Paul Giamatti (Billions, Sideways, Outsiders, Hoke), Dan Carey (Outsiders, Hoke, John Dies at the End, All Is Bright) and Jeff Freilich (Halt and Catch Fire, Grace and Frankie). Lodge 49 is an AMC Studios production.About AMCAMC is home to some of the most popular and acclaimed programs on television. AMC was the first basic cable network to ever win the Emmy(R) Award for Outstanding Drama Series with Mad Men in 2008, which then went on to win the coveted award four years in a row, before Breaking Bad won it in 2013 and 2014. The network's series The Walking Dead is the highest-rated series in cable history. AMC's other current original drama series include Better Call Saul, Fear the Walking Dead, The Terror, Into the Badlands, Preacher, The Son, Lodge 49, The Little Drummer Girl and NOS4A2. AMC also explores authentic worlds and discussion with original shows like Talking Dead, AMC Visionaries and Ride with Norman Reedus. AMC is owned and operated by AMC Networks Inc. and its sister networks include IFC, SundanceTV, BBC America and WE tv. AMC is available across all platforms, including on-air, online, on demand and mobile.About BBC AMERICABBC AMERICA is a hub of innovative, culturally contagious programming including the critically acclaimed series Killing Eve starring Golden Globe(R) and SAG Award-winner Sandra Oh, Jodie Comer and from Phoebe Waller-Bridge; top-rated phenomenon Doctor Who starring Jodie Whittaker; Emmy(R) and IDA-winning Planet Earth II and the producers' next epic story of our planet, Dynasties; Emmy(R)-winning Blue Planet II; acclaimed drama Luther starring Golden Globe(R)-winner Idris Elba; ground-breaking unscripted series Top Gear; buzzy and hilarious The Graham Norton Show; and the world's biggest darts championships. A joint venture between AMC Networks and BBC Studios (the commercial arm of the BBC), BBCA's influential shows such as Orphan Black and Broadchurch, among many others, have attracted critical acclaim and earned Emmy(R) Awards, Peabody Awards, Critics' Choice Awards, TCA Awards, Gotham Award and Golden Globes(R). Created in 1998, the irrepressible network has garnered one of cable's most curious, educated and affluent audiences, with many properties boasting super-fan levels of engagement. Get caught up, BBCA offers full episodes On Demand across all major digital platforms, BBC AMERICA app and bbcamerica.com. Find out more by visiting press.bbcamerica.com.BBCA on social: YouTube - Twitter - Instagram - Facebook - TumblrAbout Sundance NowSundance Now is AMC Networks' premium streaming service, offering original and exclusive dramas, comedies, and true crime series, in addition to award-winning movies from every genre, including foreign-language and documentary features - all streaming commercial-free. Built on the Sundance legacy, Sundance Now is proud to present an extensive array of entertainment for a passionate and intellectually curious audience. Follow Sundance Now on Twitter@sundance_now, Facebook@SundanceNow, Instagram@SundanceNow and YouTube@Sundance NowShare| 2b1af7f3a8